Helle S. Waagepetersen
Guest Researcher
Department of Drug Design and Pharmacology
Jagtvej 160
2100 København Ø
- 2017
- Published
Alterations in Cerebral Cortical Glucose and Glutamine Metabolism Precedes Amyloid Plaques in the APPswe/PSEN1dE9 Mouse Model of Alzheimer's Disease
Andersen, Jens Velde, Christensen, S. K., Aldana, Blanca, Nissen, J. D., Tanila, H. & Waagepetersen, Helle S., Jun 2017, In: Neurochemical Research. 42, 6, p. 1589–1598Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Citrate, a Ubiquitous Key Metabolite with Regulatory Function in the CNS
Westergaard, N., Waagepetersen, Helle S., Belhage, B. & Schousboe, Arne, Jun 2017, In: Neurochemical Research. 42, 6, p. 1583-1588 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved cerebral energetics and ketone body metabolism in db/db mice
Andersen, Jens Velde, Christensen, S. K., Nissen, J. D. & Waagepetersen, Helle S., Mar 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 3, p. 1137–1147 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The tricarboxylic acid cycle activity in cultured primary astrocytes is strongly accelerated by the protein tyrosine kinase inhibitor tyrphostin 23
Hohnholt, M. C., Blumrich, E., Waagepetersen, Helle S. & Dringen, R., Jan 2017, In: Neurochemistry International. 102, p. 13-21Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons
Aldana, Blanca, Zhang, Y., Lihme, M. F., Bak, Lasse Kristoffer, Nielsen, Jørgen Erik, Holst, B., Hyttel, P., Freude, Kristine & Waagepetersen, Helle S., 2017, In: Neurochemistry International. 106, p. 48-61Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the L-glutamate clearance pathways across the blood-brain barrier and the effect of astrocytes in an in vitro blood-brain barrier model
Helms, H. C., Aldana, Blanca, Groth, S., Jensen, M. M., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 12, p. 3744–3758Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes
Nissen, J. D., Lykke, K., Bryk, J., Stridh, M. H., Zaganas, I., Jensen, Dorte Skytt, Schousboe, Arne, Bak, Lasse Kristoffer, Enard, W., Pääbo, S. & Waagepetersen, Helle S., 2017, In: Glia. 65, 3, p. 474–488Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose, Lactate and Glutamine but not Glutamate Support Depolarization-Induced Increased Respiration in Isolated Nerve Terminals
Hohnholt, M. C., Andersen, V. H., Bak, Lasse Kristoffer & Waagepetersen, Helle S., 2017, In: Neurochemical Research. 42, 1, p. 191-201 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glutamate Transporters in the Blood-Brain Barrier
Helms, H. C. C., Nielsen, C. U., Waagepetersen, Helle S. & Larsen, Birger Brodin, 2017, Glial Amino Acid Transporters. Vol. 16. p. 297-314 18 p. (Advances in Neurobiology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Glutamate and ATP at the Interface Between Signaling and Metabolism in Astroglia: Examples from Pathology
Parpura, V., Fisher, E. S., Lechleiter, J. D., Schousboe, Arne, Waagepetersen, Helle S., Brunet, S., Baltan, S. & Verkhratsky, A., 2017, In: Neurochemical Research. 42, 1, p. 19-34 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired Hippocampal Glutamate and Glutamine Metabolism in the db/db Mouse Model of Type 2 Diabetes Mellitus
Andersen, Jens Velde, Nissen, J. D., Christensen, S. K., Markussen, K. H. & Waagepetersen, Helle S., 2017, In: Neural Plasticity. 2017, p. 2107084 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic Characterization of Acutely Isolated Hippocampal and Cerebral Cortical Slices Using [U-(13)C]Glucose and [1,2-(13)C]Acetate as Substrates
McNair, Laura M., Kornfelt, R., Walls, Anne Byriel, Andersen, Jens Velde, Aldana, B. I., Nissen, J. D., Schousboe, Arne & Waagepetersen, Helle S., 2017, In: Neurochemical Research. 42, 3, p. 810-826 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial function in Müller cells - Does it matter?
Toft-Kehler, A. K., Jensen, Dorte Skytt, Svare, A., Lefevere, E., Van Hove, I., Moons, L., Waagepetersen, Helle S. & Kolko, Miriam, 2017, In: Mitochondrion. 36, p. 43-51Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
Zhang, Y., Schmid, B., Qas Younan, N. K., Rasmussen, M. A., Garcia, B. I. A., Agger, M., Callø, K., Stummann, T. C., Larsen, H. M., Nielsen, T. T., Huang, J., Xu, F., Liu, X., Bolund, L., Meyer, M., Bak, L. K., Waagepetersen, H. S., Luo, Y., Nielsen, J. E., Consortium, T. FRA. & 4 others, , 2017, In: Stem Cell Reports. 8, 3, p. 648-658Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specificity of exogenous acetate and glutamate as astrocyte substrates examined in acute brain slices from female mice using methionine sulfoximine (MSO) to inhibit glutamine synthesis
Andersen, Jens Velde, McNair, Laura M., Schousboe, Arne & Waagepetersen, Helle S., 2017, In: Journal of Neuroscience Research. 95, 11, p. 2207-2216Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Glutamate oxidation in astrocytes: Roles of glutamate dehydrogenase and aminotransferases
McKenna, M. C., Stridh, M. H., McNair, Laura M., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 15 Sep 2016, In: Journal of Neuroscience Research. 94, 12, p. 1561-1571 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modeling the ischemic blood-brain barrier; the effects of oxygen-glucose deprivation (OGD) on endothelial cells in culture
Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig, Waagepetersen, Helle S. & Larsen, Birger Brodin, 19 Jun 2016.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
ATP induce intracellular calcium rises in cultures of primary brain pericytes
Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jun 2016.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Neuronal Cell Death Induced by Mechanical Percussion Trauma in Cultured Neurons is not Preceded by Alterations in Glucose, Lactate and Glutamine Metabolism
Jayakumar, A. R., Bak, Lasse Kristoffer, Rama Rao, K. V., Waagepetersen, Helle S., Schousboe, Arne & Norenberg, M. D., Feb 2016, In: Neurochemical Research. 41, 1, p. 307-15 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Anaplerosis for Glutamate Synthesis in the Neonate and in Adulthood
Brekke, E., Morken, T. S., Walls, Anne Byriel, Waagepetersen, Helle S., Schousboe, Arne & Sonnewald, U., 2016, The Glutamate/ GABA- Glutamine Cycle : Amino Acid Neurotransmitter Homeostasis. Springer, Vol. 13. p. 43-58 16 p. (Advances in Neurobiology, Vol. 13).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Chronic pyruvate supplementation increases exploratory activity and brain energy reserves in young and middle-aged mice
Koivisto, H., Leinonen, H., Puurula, M., Hafez, H. S., Barrera, G. A., Stridh, M. H., Waagepetersen, Helle S., Tiainen, M., Soininen, P., Zilberter, Y. & Tanila, H., 2016, In: Frontiers in Aging Neuroscience. 8, p. 1-14 14 p., 41.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rises in intracellular calcium in primary brain pericytes are caused by ATP
Jensen, S. H., Helms, H. C. C., Cai, Changsi, Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2016. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- 2015
- Published
Dynamic changes in cytosolic ATP levels in cultured glutamatergic neurons during NMDA-induced synaptic activity supported by glucose or lactate
Lange, S. C., Winkler, U., Andresen, Lars, Byhrø, M., Waagepetersen, Helle S., Hirrlinger, J. & Bak, Lasse Kristoffer, Dec 2015, In: Neurochemical Research. 40, 12, p. 2517-2526 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dysfunctional TCA-Cycle Metabolism in Glutamate Dehydrogenase Deficient Astrocytes
Nissen, J. D., Pajęcka, K., Stridh, M. H., Jensen, Dorte Skytt & Waagepetersen, Helle S., Dec 2015, In: Glia. 63, 12, p. 2313-26 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 983216
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Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
Research output: Contribution to journal › Journal article › Research › peer-review
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Lactate-Mediated Protection of Retinal Ganglion Cells
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Distinct differences in rates of oxygen consumption and ATP synthesis of regionally isolated non-synaptic mouse brain mitochondria
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