Helle S. Waagepetersen
Guest Researcher
Department of Drug Design and Pharmacology
Jagtvej 160
2100 København Ø
- 2013
- Published
Astrocytic control of biosynthesis and turnover of the neurotransmitters glutamate and GABA
Schousboe, Arne, Bak, Lasse Kristoffer & Waagepetersen, Helle S., 15 Aug 2013, In: Frontiers in Endocrinology. 4, 102.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures
Dadsetan, S., Kukolj, E., Bak, Lasse Kristoffer, Sørensen, M., Ott, P., Vilstrup, H., Schousboe, Arne, Keiding, S. & Waagepetersen, Helle S., Aug 2013, In: Journal of Cerebral Blood Flow and Metabolism. 33, 8, p. 1235-41 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry
Müller, M. S., Obel, L. L. F., Waagepetersen, Helle S., Schousboe, Arne & Bak, Lasse Kristoffer, Jun 2013, In: Neurochemical Research. 38, 6, p. 1260-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of pH and ADP on ammonia affinity for human glutamate dehydrogenases
Zaganas, I., Pajecka, K., Nielsen, C. W., Schousboe, Arne, Waagepetersen, Helle S. & Plaitakis, A., Jun 2013, In: Metabolic Brain Disease. 28, 2, p. 127-131 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Excitatory amino acid transporter-1 (EAAT1) is the main transporter responsible for abluminal uptake of L-glutamate in bovine brain endothelial cells
Helms, H. C. C., Groth, S., Mikél, M., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 27 May 2013.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Glutamate dehydrogenase Isoforms with N-Terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization
Pajecka, K., Nielsen, C. W., Hauge, A., Zaganas, I., Bak, Lasse Kristoffer, Schousboe, Arne, Plaitakis, A. & Waagepetersen, Helle S., 26 Apr 2013, In: Neurochemical Research. 39, 3, p. 487-499Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic encephalopathy is associated with decreased cerebral oxygen metabolism and blood flow, not increased ammonia uptake
Dam, G., Keiding, S., Munk, O. L., Ott, P., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Sørensen, M., Jan 2013, In: Hepatology. 57, 1, p. 258-65 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amino acid neurotransmitter synthesis and removal
Schousboe, Arne, Bak, Lasse Kristoffer, Madsen, K. K. & Waagepetersen, Helle S., 2013, Neuroglia. Kettenman, H. & Ransom, B. R. (eds.). 3. ed. Oxford: Oxford University Press, p. 443-456 14 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Cellemodel af blodhjernebarrieren kan mindske brugen af forsøgsdyr
Larsen, Birger Brodin, Helms, H. C. C., Hersom, M. N. S., Nielsen, C. U. & Waagepetersen, Helle S., 2013, In: Lægemiddelforskning. 2013, p. 47-49 3 p.Research output: Contribution to journal › Journal article › Communication
- Published
Interorgan metabolism of ornithine phenylacetate (OP)-A novel strategy for treatment of hyperammonemia
Dadsetan, S., Sørensen, M., Bak, Lasse Kristoffer, Vilstrup, H., Ott, P., Schousboe, Arne, Jalan, R., Keiding, S. & Waagepetersen, Helle S., 2013, In: Biochemical Pharmacology. 85, 1, p. 115-23 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to letter to the editor by Zheng G et al. Venous blood ammonia can be associated with cerebral blood flow in hepatic encephalopathy
Dam, G., Keiding, S., Munk, O. L., Ott, P., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Sørensen, M., 2013, In: Hepatology. 58, 2, p. 833-834Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2012
- Published
Energy Metabolism of the Brain
McKenna, M. C., Dienel, G. A., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 1 Dec 2012, Basic Neurochemistry. Elsevier, p. 200-231 32 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission
Frigerio, F., Karaca, M., De Roo, M., Mlynárik, V., Jensen, Dorte Skytt, Carobbio, S., Pajęcka, K., Waagepetersen, Helle S., Gruetter, R., Muller, D. & Maechler, P., Nov 2012, In: Journal of Neurochemistry. 123, 3, p. 342-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Primary cultures of astrocytes: their value in understanding astrocytes in health and disease
Lange, S. C., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Norenberg, M. D., Nov 2012, In: Neurochemical Research. 37, 11, p. 2569-88 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase
Vetterli, L., Carobbio, S., Pournourmohammadi, S., Martin-Del-Rio, R., Jensen, Dorte Skytt, Waagepetersen, Helle S., Tamarit-Rodriguez, J. & Maechler, P., Oct 2012, In: Molecular Biology of the Cell. 23, 19, p. 3851-62 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro evidence for the brain glutamate efflux hypothesis: brain endothelial cells co-cultured with astrocytes display a polarized brain-to-blood transport of glutamate
Helms, H. C. C., Madelung, R., Groth, S., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 13 Sep 2012. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Importance of glutamate dehydrogenase, GDH, in astrocyte metabolism for maintenance of glutamate and energy homeostasis
Waagepetersen, Helle S., 29 Jun 2012, København. 66 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Brain glycogen: new perspectives on its metabolic function and regulation at the subcellular level
Obel, L. L. F., Müller, M. S., Walls, Anne Byriel, Sickmann, H. M., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2 Mar 2012, In: Frontiers in Neuroenergetics. 4, 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation
Kreft, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2012, In: A S N Neuro. 4, 3, p. 187 199 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Brain energy and ammonia metabolism
Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2012, Functional molecular imaging in hepatology. Bentham Science Publishers, Vol. 1. p. 129-144 16 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Brain glycogen and its role in supporting glutamate and GABA homeostasis in a type 2 diabetes rat model
Sickmann, H. M., Waagepetersen, Helle S., Schousboe, Arne, Benie, A. J. & Bouman, S. D., 2012, In: Neurochemistry International. 60, 3, p. 267-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission
Frigerio, F., Karaca, M., De Roo, M., Mlynarik, V., Jensen, Dorte Skytt, Carobbio, S., Pajecka, K., Waagepetersen, Helle S., Gruetter, R., Muller, D. & Maechler, P., 2012, In: Journal of Neurochemistry. 123, 3, p. 342-348Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delineation of glutamate pathways and secretory responses in pancreatic islets with ß-cell-specific abrogation of the glutamate dehydrogenase.
Vetterli, L., Carobbio, S., Pournourmohammadi, S., Martin-del-Rio, R., Jensen, Dorte Skytt, Waagepetersen, Helle S., Tamarit-Rodriguez, J. & Maechler, P., 2012, In: Molecular Biology of the Cell. 23, 19, p. 3851-62Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct measurement of backflux between oxaloacetate and fumarate following pyruvate carboxylation
Brekke, E., Walls, Anne Byriel, Nørfeldt, L., Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 2012, In: Glia. 60, 1, p. 147-58 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of adrenergic agents on intracellular ca(2+) homeostasis and metabolism of glucose in astrocytes with an emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: implications for glutamate neurotransmission and excitotoxicity
Obel, L. L. F., Andersen, K. M. H., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2012, In: Neurotoxicity Research. 21, 4, p. 405-17 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 983216
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Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
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Lactate-Mediated Protection of Retinal Ganglion Cells
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Distinct differences in rates of oxygen consumption and ATP synthesis of regionally isolated non-synaptic mouse brain mitochondria
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