Increased short- and long-term mortality following infections in dementia: a nationwide registry-based cohort study

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Increased short- and long-term mortality following infections in dementia : a nationwide registry-based cohort study. / Janbek, J.; Taudorf, L.; Musaeus, C. S.; Frimodt-Møller, N.; Laursen, T. M.; Waldemar, G.

I: European Journal of Neurology, Bind 28, Nr. 2, 2021, s. 411-420.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Janbek, J, Taudorf, L, Musaeus, CS, Frimodt-Møller, N, Laursen, TM & Waldemar, G 2021, 'Increased short- and long-term mortality following infections in dementia: a nationwide registry-based cohort study', European Journal of Neurology, bind 28, nr. 2, s. 411-420. https://doi.org/10.1111/ene.14595

APA

Janbek, J., Taudorf, L., Musaeus, C. S., Frimodt-Møller, N., Laursen, T. M., & Waldemar, G. (2021). Increased short- and long-term mortality following infections in dementia: a nationwide registry-based cohort study. European Journal of Neurology, 28(2), 411-420. https://doi.org/10.1111/ene.14595

Vancouver

Janbek J, Taudorf L, Musaeus CS, Frimodt-Møller N, Laursen TM, Waldemar G. Increased short- and long-term mortality following infections in dementia: a nationwide registry-based cohort study. European Journal of Neurology. 2021;28(2):411-420. https://doi.org/10.1111/ene.14595

Author

Janbek, J. ; Taudorf, L. ; Musaeus, C. S. ; Frimodt-Møller, N. ; Laursen, T. M. ; Waldemar, G. / Increased short- and long-term mortality following infections in dementia : a nationwide registry-based cohort study. I: European Journal of Neurology. 2021 ; Bind 28, Nr. 2. s. 411-420.

Bibtex

@article{9e034a428c2a45adb376c5388955061f,
title = "Increased short- and long-term mortality following infections in dementia: a nationwide registry-based cohort study",
abstract = "Background and purpose: Mortality following infections in dementia has not yet been comprehensively explored. The aim of this cohort study was to investigate the short- and long-term mortality following infections in dementia. Methods: Follow-up was from 1 January 2000 or the 65-year birthday until death, immigration, or 31 December 2015. Exposure was incident dementia and a first infection. The outcome was all-cause mortality. Mortality rate ratios (MRRs) were calculated using Poisson regression in 4 exposure groups (dementia yes/no, infection yes/no) by sex, infection site, and time since infection. Results: 1,496,436 people were followed with 12,739,135 person-years. MRR in dementia/infection was 6.52 (95% confidence interval: 6.43–6.60) and was increased for infections of all sites. Increased mortality was short term (30 days) and long term (10 years). Conclusions: Increased mortality in people with dementia identifies them as a particularly vulnerable group that needs clinical attention.",
keywords = "dementia, epidemiology, infection, mortality, registry-based study",
author = "J. Janbek and L. Taudorf and Musaeus, {C. S.} and N. Frimodt-M{\o}ller and Laursen, {T. M.} and G. Waldemar",
year = "2021",
doi = "10.1111/ene.14595",
language = "English",
volume = "28",
pages = "411--420",
journal = "European Journal of Neurology",
issn = "1351-5101",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - Increased short- and long-term mortality following infections in dementia

T2 - a nationwide registry-based cohort study

AU - Janbek, J.

AU - Taudorf, L.

AU - Musaeus, C. S.

AU - Frimodt-Møller, N.

AU - Laursen, T. M.

AU - Waldemar, G.

PY - 2021

Y1 - 2021

N2 - Background and purpose: Mortality following infections in dementia has not yet been comprehensively explored. The aim of this cohort study was to investigate the short- and long-term mortality following infections in dementia. Methods: Follow-up was from 1 January 2000 or the 65-year birthday until death, immigration, or 31 December 2015. Exposure was incident dementia and a first infection. The outcome was all-cause mortality. Mortality rate ratios (MRRs) were calculated using Poisson regression in 4 exposure groups (dementia yes/no, infection yes/no) by sex, infection site, and time since infection. Results: 1,496,436 people were followed with 12,739,135 person-years. MRR in dementia/infection was 6.52 (95% confidence interval: 6.43–6.60) and was increased for infections of all sites. Increased mortality was short term (30 days) and long term (10 years). Conclusions: Increased mortality in people with dementia identifies them as a particularly vulnerable group that needs clinical attention.

AB - Background and purpose: Mortality following infections in dementia has not yet been comprehensively explored. The aim of this cohort study was to investigate the short- and long-term mortality following infections in dementia. Methods: Follow-up was from 1 January 2000 or the 65-year birthday until death, immigration, or 31 December 2015. Exposure was incident dementia and a first infection. The outcome was all-cause mortality. Mortality rate ratios (MRRs) were calculated using Poisson regression in 4 exposure groups (dementia yes/no, infection yes/no) by sex, infection site, and time since infection. Results: 1,496,436 people were followed with 12,739,135 person-years. MRR in dementia/infection was 6.52 (95% confidence interval: 6.43–6.60) and was increased for infections of all sites. Increased mortality was short term (30 days) and long term (10 years). Conclusions: Increased mortality in people with dementia identifies them as a particularly vulnerable group that needs clinical attention.

KW - dementia

KW - epidemiology

KW - infection

KW - mortality

KW - registry-based study

U2 - 10.1111/ene.14595

DO - 10.1111/ene.14595

M3 - Journal article

C2 - 33065766

AN - SCOPUS:85096708310

VL - 28

SP - 411

EP - 420

JO - European Journal of Neurology

JF - European Journal of Neurology

SN - 1351-5101

IS - 2

ER -

ID: 252722642