Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity
Research output: Contribution to journal › Journal article › Research › peer-review
Peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) is a recently identified homologue of the tissue specific coactivator PGC-1alpha, a coactivator of transcription factors such as the peroxisome proliferators activated receptors and nuclear respiratory factors. PGC-1alpha is involved in adipogenesis, mitochondrial biogenesis, fatty acid beta oxidation, and hepatic gluconeogenesis.
| Original language | English |
|---|---|
| Journal | Journal of Medical Genetics |
| Volume | 42 |
| Issue number | 5 |
| Pages (from-to) | 402-7 |
| Number of pages | 6 |
| ISSN | 1468-6244 |
| DOIs | |
| Publication status | Published - 1 May 2005 |
- Aged, Carrier Proteins, DNA Mutational Analysis, Denmark, Diabetes Mellitus, Type 2, Gene Frequency, Genetic Testing, Genetic Variation, Genotype, Glucose, Humans, Linkage Disequilibrium, Middle Aged, Mutation, Obesity
Research areas
ID: 33030532