Opioid dispensing in relation to arthroscopic knee surgery in Denmark from 2006 to 2018
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Opioid dispensing in relation to arthroscopic knee surgery in Denmark from 2006 to 2018. / Thorlund, Jonas Bloch; Lundberg, Matilde; Petersen, Jindong Ding; Englund, Martin; Viberg, Bjarke; Waldorff, Frans Boch; Søndergaard, Jens.
In: Danish Medical Journal, Vol. 70, No. 9, A01230032, 2023.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Opioid dispensing in relation to arthroscopic knee surgery in Denmark from 2006 to 2018
AU - Thorlund, Jonas Bloch
AU - Lundberg, Matilde
AU - Petersen, Jindong Ding
AU - Englund, Martin
AU - Viberg, Bjarke
AU - Waldorff, Frans Boch
AU - Søndergaard, Jens
N1 - Articles published in the DMJ are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
PY - 2023
Y1 - 2023
N2 - INTRODUCTION: In the US, opioids are commonly prescribed after arthroscopic knee surgery. We aimed to investigate opioid dispensing in relation to arthroscopic knee surgeries from 2006 to 2018 in Denmark.METHODS: In Danish registries, we identified patients (≥ 15 years old) having arthroscopic knee surgery (anterior cruciate ligament (ACL) reconstruction; meniscal surgery; cartilage resection; synovectomy and diagnostic arthroscopy) between 1 January 2006 and 31 December 2018 and opioid dispensing (oral morphine equivalents (OMEQ)) within seven days after discharge from surgery.RESULTS: Among 218,940 patients, 15,263 (7%) had an opioid dispensed within seven days after being discharged following surgery. The opioid dispensing incidence (per 1,000 persons/year) increased during the study period for all procedures. This trend was more pronounced for ACL reconstruction, which recorded an increase from 86 (95% confidence interval (CI): 75-99) in 2006 to 278 (95% CI: 255-301) in 2018, corresponding to 9% and 28% of ACL patients, respectively. In the same period, the average amount of opioids dispensed within the first seven days after discharge decreased (change: 70.0 OMEQ (95% CI: 12.4-127.5)). Tramadol and oxycodone were the most commonly dispensed opioids.CONCLUSION: About 7% of patients had an opioid dispensed within the first seven days after discharge following arthroscopic knee surgery. The incidence of opioids dispensed increased for all investigated procedures from 2006 to 2018. In the same period, the average amount of opioids dispensed within the first seven days after discharge decreased.FUNDING: None.TRIAL REGISTRATION: Not relevant.
AB - INTRODUCTION: In the US, opioids are commonly prescribed after arthroscopic knee surgery. We aimed to investigate opioid dispensing in relation to arthroscopic knee surgeries from 2006 to 2018 in Denmark.METHODS: In Danish registries, we identified patients (≥ 15 years old) having arthroscopic knee surgery (anterior cruciate ligament (ACL) reconstruction; meniscal surgery; cartilage resection; synovectomy and diagnostic arthroscopy) between 1 January 2006 and 31 December 2018 and opioid dispensing (oral morphine equivalents (OMEQ)) within seven days after discharge from surgery.RESULTS: Among 218,940 patients, 15,263 (7%) had an opioid dispensed within seven days after being discharged following surgery. The opioid dispensing incidence (per 1,000 persons/year) increased during the study period for all procedures. This trend was more pronounced for ACL reconstruction, which recorded an increase from 86 (95% confidence interval (CI): 75-99) in 2006 to 278 (95% CI: 255-301) in 2018, corresponding to 9% and 28% of ACL patients, respectively. In the same period, the average amount of opioids dispensed within the first seven days after discharge decreased (change: 70.0 OMEQ (95% CI: 12.4-127.5)). Tramadol and oxycodone were the most commonly dispensed opioids.CONCLUSION: About 7% of patients had an opioid dispensed within the first seven days after discharge following arthroscopic knee surgery. The incidence of opioids dispensed increased for all investigated procedures from 2006 to 2018. In the same period, the average amount of opioids dispensed within the first seven days after discharge decreased.FUNDING: None.TRIAL REGISTRATION: Not relevant.
KW - Humans
KW - Adolescent
KW - Analgesics, Opioid/therapeutic use
KW - Arthroscopy
KW - Tramadol
KW - Patient Discharge
KW - Denmark/epidemiology
UR - https://ugeskriftet.dk/dmj/opioid-dispensing-relation-arthroscopic-knee-surgery-denmark-2006-2018
M3 - Journal article
C2 - 37622647
VL - 70
JO - Danish Medical Journal
JF - Danish Medical Journal
SN - 2245-1919
IS - 9
M1 - A01230032
ER -
ID: 384862782